How does our site make you feel?
Great   Indifferent

Glucosamine and Chondroitin Sulfate

Glucosamine and Chondroitin Sulfate are over-the-counter nutritional supplements commonly used to treat osteoarthritis. In contrast to many over-the-counter supplements, Glucosamine and Chondroitin Sulfate have been fairly well studied and favorable results have been found by independent researchers. This is in marked contrast to most nutritional supplements where there is no scientific evidence of benefit.

Glucosamine and Chondroitin are chemicals that the joint cartilage can use as a building block to try to maintain the cartilage’s health. There is also some evidence that the substances act as anti inflammatories. Overall, they seem to be fairly safe and most commercial preparations provide comparable efficacy. Of note, the ideal dosages of Glucosamine and Chondroitin are unknown.


  1. Improvement in symptoms may not be seen for a few months. It requires a steady intake in order for these substances to be effective. This can be somewhat expensive during this trial period when you are unsure if it will actually work.
  2. Glucosamine is derived from the shells of shellfish. If you are allergic to shellfish, you should be cautious using preparations containing Glucosamine. However, to my knowledge, there have been no reports of allergic reactions.
  3. Chondroitin comes from the cartilage of cows, steers, and bulls. It is theoretically possible that diseases such as Bovine Spongiform Encephalopathy and Creutzfeldt-Jakob disease could be transmitted. I emphasize that this has never occurred, but since the supplement industry is not under the supervision of the FDA, it is poorly regulated and quality control is unpredictable.
  4. If you have diabetes, you should monitor your blood glucose levels more closely when using Glucosamine. It has been shown to affect insulin resistance.
  5. Chondroitin can cause bleeding in people who already have bleeding disorders or those that take blood-thinning medications such as Coumadin or heparin preparations.

Overall, these preparations seem to be extremely safe. Disease transmission has never been reported.

Read more about Glucosamine and Chondroitin Sulfate on the American Academy of Orthopaedic Surgeons (AAOS) website.

For more information on throwing injuries please visit:

You Might Also Enjoy...

Our Favorite Off-Season Training Tips

As an athlete, you need to stay in shape all year, whether in-season or not. How do you keep fit and strong when your coach isn’t on your case? The following are tips to stay on top of your game.

Diet Hacks to Keep Your Joints in Game Time Condition

Pro athletes must keep their joints in top condition to stay in the game. That’s why they’re ahead of the curve regarding preventive strategies and cutting-edge therapies. The following are some of their top diet hacks.

How to Workout When Your Arm Is in a Cast/brace

Sports and injuries go hand-in-hand. In fact, if you play sports, you’re more likely to break a bone. But you’re also more eager to stay in shape. How do you do that with an arm in a cast or brace?

3 Knee Protection Tips Every Basketball Player Should Know

Stopping short. Jumping high. Pivoting. All the moves of an exciting basketball game put tremendous stress on your knees. If you blow out your knee, you could be sitting on the sidelines for months or years. How do you keep your knees safe?

Want to Avoid Tommy John? Start Doing This Today

If you throw for your sport or your living, the last thing you want to do is throw out your arm by tearing the ulnar collateral ligament (UCL) in your elbow. Although Tommy John surgery repairs torn UCLs, the best treatment is prevention.

Signs Your Shoulder Isn't Stable

As an athlete, you need to be aware of your body, its mechanics, and its needs. If you play sports that involve throwing or hitting, you may develop an unstable shoulder. Know the signs of shoulder instability to avoid further injury.